Discipline: Preventive Veterinary Medicine E-Mail: dhe@scau.edu.cn Address: College of Veterinary Medicine, South China Agricultural University, Guangzhou province 510642
Resume:
Dongsheng He,Male,Born in1968. Ph.D. in Agriculture, Professor, Ph.D tutor.
National Committee Member or Veterinary Vaccine Evaluation
He received the Master's degree in Veterinary Epidemiology in 1992 and Ph.D in 1998. He is a teacher since 1992 at South China Agricultural University. He was promoted to a professor in 2015.
He has published more than 100 papers and books. He has won the First Prize award of Science and Technology of Guangdong province and Ministry of Education.
Education and Training Program:
July 1995-June 1998: PhD. Candidate, College of Veterinary Medicine, South China Agricultural University
July 1989-June 1992: Master degree candidate, Animal Medicine Department of Guangxi Agricultural University
July 1985-June 1989: Undergraduate, Veterinary Department of Guangxi Agricultural University
Research Interests:
Veterinary Epidemiology; Swine Diseases; Vaccine Development; Diagnosis and Prevention of Animal Diseases
Grants:
1.Natural Science Foundation of China(NSFC): mechanism of PRRSV immune resistance , 2014-2016
2.Porcine Delta Corovirus isolation,detection and vaccine development granted by Guangdong province
3.Swine diseases detection and prevention in Guangdong Province. 2016-2020. Granted by GD Province
4.SVV/SVA isolation and vaccine development,granted by two company.
5.PRRSVs monitoring and vaccine development,granted by two company.
6.etc
Publications:
1.Zhixuan Xiong, Xiaoyun Niu,Yabing Song, Danping Su, Fei Wang, Rui-ai Chen, Dongsheng He. Evolution of porcine reproductive and respiratory syndrome virus GP5 and GP3 genes under swIFN-â immune pressure and interferon regulatory factor-3 activation suppressed by GP5. Research in Veterinary Science.101(2015): 175-179.
2.Chao-Nan Lin 1,2† , Yu-Jian Yang 3† , Wei-Hao Lin 1 , Hsien-Ching Wu 4 , Zhixuan Xiong 5 , Wouter Depondt 6 ,Alain Kanora 6 , Min Cui 7 , Danping Su 5 , Dongsheng He & Ming-Tang Chiou Tilmicosin Reduces PRRSV Loads in Pigs in vivo. Journal of Agricultural Science; 2016.Vol( 8)1;154-162
3. Amy Galliher-Beckley, Xiangdong Li, John T. Bates, Rachel Madera, Andrew Waters, Jerome Nietfeld, Jamie Henningson, Dongsheng He, Wenhai Feng, Ruiai Chen, Jishu Shi. Pigs immunized with Chinese highly pathogenic PRRS virus modified live vaccine are protected from challenge with North American PRRSV strain NADC-20. Vaccine. 33(2015)3518-3525.
4.Xiao-Peng Li,Shao-Lun Zha,Dong-Sheng He • Peng-Ju Guo,Dian-Hong Lv ,Xiao-Hui Wen, Man-Lin Luo, Rui-Ai Chen,Wen-Kang Wei. Genome characterization and phylogenetic analysis of a lineage IV peste des petits ruminants virus in southern China. Virus Genes (2015) 51:361–366
5.Shao-Lun Zhai, Dong-Sheng He, Wen-Bao Qi, Sheng-Nan Chen, Su-Fang Deng, Jun Hu, Xiao-Peng Li, Lei Li, Rui-Ai Chen, Man-Lin Luo. Complete genome characterization and phylogenetic analysisof three distinct buffalo一origin PCV2 isolates from China. Infection, Genetics and Evolution. 28 (2014) 278-282
6.Construction of the Fusion Protoplast of Swine Escherichia coli with Hemophilus parasuis. J. of Animal & Vet. Advances.2014.01
7.Shao-Lun Zhai, Rui-Ai Chen,Sheng-Nan Chen,Xiao-Hui Wen, Dian-Hong Lv,Da-Cheng Wu,Jie Yuan,Zhong Huang,Xiu-Rong Zhou,Man-Lin Luo,Dong-Sheng He•, Wen-Kang Wei. First molecular detection of porcine circovirus type 2 in bovids in China.Virus Genes, (2014) 49:507–511. IF 1.837
8.Dongsheng He , Xiaoyun Niu, Aixiang Jiang,etc. swIFN-â promotes genetic mutation of porcine reproductive and respiratory syndrome virus in Marc-145. Veterinary Microbiology. 166 (2013)174–178
9.Complete Genome Sequence of a Very Virulent Porcine Epidemic Diarrhea Virus Strain, CH/GDGZ/2012, Isolated in Southern China. Genome Announcement. 2013.08.
10.Prevalence and Characterization of serotype and out Membrane Protein Diversity of Escherichia coli Isolated from Southern China. J. of Animal & Vet. Advances. 2013.12.
11.Dong-Sheng He , Kang-Ning Li, Xiao-Min Lin,etc. Genomic comparison of FMDV R strain and its chick-passaged attenuated strain. Veterinary Microbiology, (2011)185-190.
12.D. He, C. Overend, J. Ambrogio, A.E. Garmendia etc. Marked differences between MARC-145 cells and swine alveolar macrophages in IFNâinduced activation of antiviral state against PRRSV. Vet. Immun. & Immunopath, 2011(139):57–60.
13.Dongsheng He,Ning Z, Yu X, Liao M,etc,Porcine IFN-beta is biologically active and secreted in the yeast pichia expression system. J. of Animal & Vet. Advances. 2011.7
14.Dongsheng He, Zhao Y, Su,D,etc., Development if PCR for the identification of PCV-2 genotype PCV-2a and PCV-2b. J. of Animal & Vet. Advances. 2011.7
15.Dongsheng He, Ruizhen Rachel Chen. Functional expression of heterologous UDP-galactose-4-epimerase in Agrobacterium sp. via a broad host-range expression vector. Biotechnology Letters. 2002(124):1599-1603.