Resume:

Cao-Weisheng，Born in Sept, 1975, Ph.D.in Preventive Veterinary Medicine, Professor. Dr Cao received his Master Degree and Ph.D Degree in 2001 and 2004 respectively in South China Agricultural University（SCAU）. He received professor position at South China Agricultural University in 2016. Dr Cao has been working on avian tumor diseases for more than twelve years. His research has focused on epidemiology, infection and immunity, molecular tumorigenesis and control & eradication of avian leukosis, has significantly contributed to the exogenous ALV eradication project in Guangdong Province. He has published 20 SCI papers including JVI, JGVand SCI Rep. He is currently also paying more attention to avian egg-borne diseases. 

Education and Training Program:

　　May, 2011-May, 2012: Visiting Scholar, Avian diseases and Oncology Laboratory (ARS-ADOL), MI, USA

September, 2001-June, 2004: PhD. Preventive Veterinary Medicine, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

September, 1998-June, 2001: M.S., Preventive Veterinary Medicine, College of Veterinary Medicine, SCAU, Guangzhou, China

September, 1993-June, 1998: B.S., Veterinary Medicine, SCAU, Guangzhou, China

Working Experience:

　　July, 2004- Nove, 2006: Lecturer, Department of Animal Infectious Diseases, College of Veterinary Medicine, SCAU, Guangzhou, China.

Dece, 2006- Nove,2016, Associate Prof, Department of Animal Infectious Diseases, College of Veterinary Medicine, SCAU, Guangzhou, China.

Aug, 2016- present, Disease Control Post Expert of Guangdong Province Poultry Industry Technology System 

Dece, 2016- Present, Prof,  Department of Animal Infectious Diseases, College of Veterinary Medicine, SCAU, Guangzhou, China.

Jun, 2017- present, Ph.D supervisor, Department of Animal Infectious Diseases, College of Veterinary Medicine, SCAU, Guangzhou, China.

Feb,2018- present, Deputy director of Guangdong Provincial Key Laboratory of animal origin zoonosis prevention and control. 

Research Interests:

Epidemiology of Avian tumor diseases & avian eggborne disease; Infection mechanism, pathogenesis or tumorigenesis, control and eradication of AL and other egg-borne disease. 

Grants: 

      GD Province Poultry Industry Technology System(2016LM1114)2016.8-2021.8

The National Key R&D Project (2016YFD0501606) 2016.7-2020.12

      The National Natural Science Fund (30771612)2016.8-2020.12

       The Natural Science Foundation of Guangdong Province(2016A030313403)2016.1-2019.1

      The poultry production technology of Guangdong system(2016LM1114)2016.8-2021.7      

Key Publications:

1. Zhao Z, Rao M, Liao M, Cao W*. Phylogenetic Analysis and Pathogenicity Assessment of the Emerging Recombinant Subgroup K of Avian Leukosis Virus in South China. Viruses. 2018 Apr 13;10(4). pii: E194. doi: 10.3390/v10040194.

2. Jian Chen, Zijun Zhao, Yangyijun Chen, Jie Zhang, Lifu Yan, Xiaocui Zheng, Ming Liao, and Weisheng Cao*. Development and application of a SYBR green real-time PCR for detection of the emerging avian leukosis virus subgroup K. 2018 Poultry Science 0:1–7; http://dx.doi.org/ 10.3382/ps/pey086

3. Mingzhang R, Zijun Z, Lixia Y, Jian C, Min F, Jie Z, Ming L, Weisheng C*. The construction and application of a cell line resistant to novel subgroup avian leukosis virus (ALV-K) infection.Arch Virol. 2018 Jan;163(1):89-98. doi: 10.1007/s00705-017-3563-2. Epub 2017 Oct 6.

4.Manman Dai, Siyu Wu, Min Feng, Saixiang Feng, Chao Sun,Dayong Bai, Mingzhu Gu, Ming Liao, Weisheng Cao*. Recombinant chicken interferon-alpha inhibits the replication of exogenous avian leukosis virus (ALV) in DF-1 cells. Molecular Immunology 2016;76:62-69.

5.Manman Dai, Min Feng, Ming Liao, Weisheng Cao*.Inhibition of ERK/MAPK suppresses avian leukosis virus subgroup A and B replication.Microbial Pathogenesis 2017; 102 : 29-35.

6. Manman Dai, Min Feng, YuYe, Xiaochan Wu, Di Liu, Ming Liao & Weisheng Cao*.Exogenous avian leukosis virus induced activation of the ERK/AP1 pathway is required for virus replication and correlates with virus-induced tumorigenesis.Scientific RepoRts | 6:19226 | DOI: 10.1038/ srep19226.2016. Jan 12

7. Li Y, Liu X, Yang Z, Xu C, Liu D, Qin J, Dai M, Hao J, Feng M, Huang X, Tan L, Cao W*, Liao M*. The MYC, TERT, and ZIC1 genes are common targets of viral integration and transcriptional deregulation in avian leukosis virus subgroup J-induced myeloid leukosis.J Virol. 2014 Mar;88(6):3182-91. doi: 10.1128/JVI.02995-13. Epub 2013 Dec 26.

8. Xiaotao Zhang, Ming Liao, Peirong Jiao, Kaijian Luo, Henan Zhang, Tao Ren, guihong Zhang, Chenggang Xu, Chaoan Xin, and Weisheng Cao*. Development of a Loop-Mediated Isothermal Amplification Assay for Rapid Detection of Subgroup J Avian Leukosis Virus.Journal of clinical microbiology, June 2010, p. 2116–2121 Vol. 48, No. 6.